Sequence Detail

ID/Version

Q9Z2E5 (UniProt | EBI)

Last sequence update: 1999-05-01
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Transcription factor Atoh7 {ECO:0000305};AltName: Full=Atonal bHLH transcription factor 7 {ECO:0000312|MGI:MGI:1355553};AltName: Full=Helix-loop-helix protein mATH-5 {ECO:0000303|PubMed:9806930}; Short=mATH5 {ECO:0000303|PubMed:98069

Provider

SWISS-PROT

Sequence

Polypeptide 149 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Atoh7	atonal bHLH transcription factor 7	26	132	3	15

Sequence references in MGI

J:50518 Brown NL, et al., Math5 encodes a murine basic helix-loop-helix transcription factor expressed during early stages of retinal neurogenesis. Development. 1998 Dec;125(23):4821-33
J:67382 Wang SW, et al., Requirement for math5 in the development of retinal ganglion cells. Genes Dev. 2001 Jan 1;15(1):24-9
J:70746 Brown NL, et al., Math5 is required for retinal ganglion cell and optic nerve formation. Development. 2001 Jul;128(13):2497-508
J:75001 Brown NL, et al., Molecular characterization and mapping of ATOH7, a human atonal homolog with a predicted role in retinal ganglion cell development. Mamm Genome. 2002 Feb;13(2):95-101
J:80431 Wee R, et al., Loss of photic entrainment and altered free-running circadian rhythms in math5-/- mice. J Neurosci. 2002 Dec 1;22(23):10427-33
J:132603 Saul SM, et al., Math5 expression and function in the central auditory system. Mol Cell Neurosci. 2008 Jan;37(1):153-69
J:227078 Buhr ED, et al., Neuropsin (OPN5)-mediated photoentrainment of local circadian oscillators in mammalian retina and cornea. Proc Natl Acad Sci U S A. 2015 Oct 20;112(42):13093-8
J:308269 Brodie-Kommit J, et al., Atoh7-independent specification of retinal ganglion cell identity. Sci Adv. 2021 Mar;7(11)