Sequence Detail

ID/Version

Q9Z2A9 Q8C7B4 (UniProt | EBI)

Last sequence update: 2013-09-18
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Glutathione hydrolase 5 proenzyme; EC=3.4.19.13 {ECO:0000250|UniProtKB:P36269};AltName: Full=Gamma-glutamyl leukotrienase {ECO:0000303|PubMed:9774450}; Short=GGL {ECO:0000303|PubMed:9774450};AltName: Full=Gamma-glutamyltransf

Provider

SWISS-PROT

Sequence

Polypeptide 573 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Ggt5	gamma-glutamyltransferase 5	48	97	4	12

Sequence references in MGI

J:50497 Carter BZ, et al., gamma-glutamyl leukotrienase, a gamma-glutamyl transpeptidase gene family member, is expressed primarily in spleen. J Biol Chem. 1998 Oct 23;273(43):28277-85
J:77691 Shi ZZ, et al., Disruption of gamma-glutamyl leukotrienase results in disruption of leukotriene D(4) synthesis in vivo and attenuation of the acute inflammatory response. Mol Cell Biol. 2001 Aug;21(16):5389-95
J:78478 Han B, et al., Gamma-glutamyl leukotrienase, a novel endothelial membrane protein, is specifically responsible for leukotriene D(4) formation in vivo. Am J Pathol. 2002 Aug;161(2):481-90
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:274415 Lu E, et al., S-Geranylgeranyl-L-glutathione is a ligand for human B cell-confinement receptor P2RY8. Nature. 2019 Mar;567(7747):244-248
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:311846 Gallman AE, et al., Abcc1 and Ggt5 support lymphocyte guidance through export and catabolism of S-geranylgeranyl-l-glutathione. Sci Immunol. 2021 Jun 4;6(60)