Sequence Detail

ID/Version

Q9Z265 (UniProt | EBI)

Last sequence update: 1999-05-01
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Serine/threonine-protein kinase Chk2; EC=2.7.11.1;AltName: Full=CHK2 checkpoint homolog;AltName: Full=Checkpoint kinase 2;

Provider

SWISS-PROT

Sequence

Polypeptide 546 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Chek2	checkpoint kinase 2	67	107	3	31

Sequence references in MGI

J:61425 Matsuoka S, et al., Linkage of ATM to cell cycle regulation by the Chk2 protein kinase. Science. 1998 Dec 4;282(5395):1893-7
J:78491 Hirao A, et al., Chk2 is a tumor suppressor that regulates apoptosis in both an ataxia telangiectasia mutated (ATM)-dependent and an ATM-independent manner. Mol Cell Biol. 2002 Sep;22(18):6521-32