Sequence Detail

ID/Version

Q9Z239 (UniProt | EBI)

Last sequence update: 1999-05-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Phospholemman {ECO:0000250|UniProtKB:P56513};AltName: Full=FXYD domain-containing ion transport regulator 1 {ECO:0000312|MGI:MGI:1889273};AltName: Full=Sodium/potassium-transporting ATPase subunit FXYD1 {ECO:0000305};Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 92 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Fxyd1	FXYD domain-containing ion transport regulator 1	42	102	2	4

Sequence references in MGI

J:70803 Bogaev RC, et al., Gene structure and expression of phospholemman in mouse. Gene. 2001 Jun 13;271(1):69-79
J:97365 Jia LG, et al., Hypertrophy, increased ejection fraction, and reduced Na-K-ATPase activity in phospholemman-deficient mice. Am J Physiol Heart Circ Physiol. 2005 Apr;288(4):H1982-8
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:132321 Bell JR, et al., Characterization of the phospholemman knockout mouse heart: depressed left ventricular function with increased Na-K-ATPase activity. Am J Physiol Heart Circ Physiol. 2008 Feb;294(2):H613-21
J:164988 Garcia-Rudaz C, et al., FXYD1, a modulator of Na,K-ATPase activity, facilitates female sexual development by maintaining gonadotrophin-releasing hormone neuronal excitability. J Neuroendocrinol. 2009 Feb;21(2):108-22
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:341445 Bibert S, et al., FXYD proteins reverse inhibition of the Na+-K+ pump mediated by glutathionylation of its beta1 subunit. J Biol Chem. 2011 May 27;286(21):18562-72