Sequence Detail

ID/Version

Q9Z1T5 C7SHZ9 Q3UJA4 (UniProt | EBI)

Last sequence update: 1999-05-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Deformed epidermal autoregulatory factor 1 homolog;AltName: Full=Nuclear DEAF-1-related transcriptional regulator; Short=NUDR;

Provider

SWISS-PROT

Sequence

Polypeptide 566 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Deaf1	DEAF1, transcription factor	41	106	3	10

Sequence references in MGI

J:51686 Sugihara TM, et al., Mouse deformed epidermal autoregulatory factor 1 recruits a LIM domain factor, LMO-4, and CLIM coregulators. Proc Natl Acad Sci U S A. 1998 Dec 22;95(26):15418-23
J:88168 Hahm K, et al., Defective neural tube closure and anteroposterior patterning in mice lacking the LIM protein LMO4 or its interacting partner Deaf-1. Mol Cell Biol. 2004 Mar;24(5):2074-82
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:142812 Barker HE, et al., Deaf-1 regulates epithelial cell proliferation and side-branching in the mammary gland. BMC Dev Biol. 2008;8:94
J:151759 Yip L, et al., Deaf1 isoforms control the expression of genes encoding peripheral tissue antigens in the pancreatic lymph nodes during type 1 diabetes. Nat Immunol. 2009 Sep;10(9):1026-33
J:211699 Vulto-van Silfhout AT, et al., Mutations affecting the SAND domain of DEAF1 cause intellectual disability with severe speech impairment and behavioral problems. Am J Hum Genet. 2014 May 1;94(5):649-61
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89