Sequence Detail

ID/Version

Q9Z1E3 Q3U9W9 Q3UB40 Q80ZX5 (UniProt | EBI)

Last sequence update: 2004-10-25
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=NF-kappa-B inhibitor alpha;AltName: Full=I-kappa-B-alpha; Short=IkB-alpha; Short=IkappaBalpha;

Provider

SWISS-PROT

Sequence

Polypeptide 314 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Nfkbia	nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha	99	121	4	14

Sequence references in MGI

J:53039 Spencer E, et al., Signal-induced ubiquitination of IkappaBalpha by the F-box protein Slimb/beta-TrCP. Genes Dev. 1999 Feb 1;13(3):284-94
J:54020 Hatakeyama S, et al., Ubiquitin-dependent degradation of IkappaBalpha is mediated by a ubiquitin ligase Skp1/Cul 1/F-box protein FWD1. Proc Natl Acad Sci U S A. 1999 Mar 30;96(7):3859-63
J:54317 Yaron A, et al., Identification of the receptor component of the IkappaBalpha-ubiquitin ligase. Nature. 1998 Dec 10;396(6711):590-4
J:54855 Rupec RA, et al., Structural analysis, expression, and chromosomal localization of the mouse ikba gene. Immunogenetics. 1999 May;49(5):395-403
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89