Sequence Detail

ID/Version

Q9Z0U1 Q8K210 (UniProt | EBI)

Last sequence update: 2006-05-02
Last annotation update: 2025-06-18

Sequence description from provider

RecName: Full=Tight junction protein 2 {ECO:0000312|MGI:MGI:1341872};AltName: Full=Tight junction protein ZO-2 {ECO:0000303|PubMed:10026224};AltName: Full=Zona occludens protein 2;AltName: Full=Zonula occludens protein 2;

Provider

SWISS-PROT

Sequence

Polypeptide 1167 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Tjp2	tight junction protein 2	53	112	3	611

Sequence references in MGI

J:53203 Itoh M, et al., Characterization of ZO-2 as a MAGUK family member associated with tight as well as adherens junctions with a binding affinity to occludin and alpha catenin. J Biol Chem. 1999 Feb 26;274(9):5981-6
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:196719 Linares GR, et al., Claudin 18 is a novel negative regulator of bone resorption and osteoclast differentiation. J Bone Miner Res. 2012 Jul;27(7):1553-65
J:227841 Kazmierczak M, et al., Progressive Hearing Loss in Mice Carrying a Mutation in Usp53. J Neurosci. 2015 Nov 25;35(47):15582-98
J:263376 Trinidad JC, et al., Comprehensive identification of phosphorylation sites in postsynaptic density preparations. Mol Cell Proteomics. 2006 May;5(5):914-22
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89