Sequence Detail

ID/Version

Q9Z0L3 Q9CZ60 Q9Z225 (UniProt | EBI)

Last sequence update: 2001-12-05
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Otoconin-90; Short=Oc90;AltName: Full=Otoconin-95 {ECO:0000303|PubMed:9892667}; Short=Oc95 {ECO:0000303|PubMed:9892667};Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 485 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Oc90	otoconin 90	19	116	3	13

Sequence references in MGI

J:51670 Wang Y, et al., Otoconin-90, the mammalian otoconial matrix protein, contains two domains of homology to secretory phospholipase A2. Proc Natl Acad Sci U S A. 1998 Dec 22;95(26):15345-50
J:52192 Verpy E, et al., Characterization of otoconin-95, the major protein of murine otoconia, provides insights into the formation of these inner ear biominerals. Proc Natl Acad Sci U S A. 1999 Jan 19;96(2):529-34
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:122533 Zhao X, et al., Gene targeting reveals the role of Oc90 as the essential organizer of the otoconial organic matrix. Dev Biol. 2007 Apr 15;304(2):508-24
J:240919 Yang H, et al., Matrix recruitment and calcium sequestration for spatial specific otoconia development. PLoS One. 2011;6(5):e20498
J:263439 Deans MR, et al., Mammalian Otolin: a multimeric glycoprotein specific to the inner ear that interacts with otoconial matrix protein Otoconin-90 and Cerebellin-1. PLoS One. 2010 Sep 15;5(9):e12765
J:263462 Moreland KT, et al., In vitro calcite crystal morphology is modulated by otoconial proteins otolin-1 and otoconin-90. PLoS One. 2014;9(4):e95333