Sequence Detail

ID/Version

Q9Z0I7 (UniProt | EBI)

Last sequence update: 1999-05-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Schlafen family member 1 {ECO:0000305}; Short=Schlafen-1 {ECO:0000303|PubMed:9846487};

Provider

SWISS-PROT

Sequence

Polypeptide 337 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Slfn1	schlafen 1	21	97	2	8

Sequence references in MGI

J:51308 Schwarz DA, et al., Schlafen, a new family of growth regulatory genes that affect thymocyte development. Immunity. 1998 Nov;9(5):657-68
J:101034 Brady G, et al., Schlafen-1 causes a cell cycle arrest by inhibiting induction of cyclin D1. J Biol Chem. 2005 Sep 2;280(35):30723-34
J:138087 Zhang Y, et al., The Hsp40 family chaperone protein DnaJB6 enhances Schlafen1 nuclear localization which is critical for promotion of cell-cycle arrest in T-cells. Biochem J. 2008 Jul 15;413(2):239-50