Sequence Detail

ID/Version

Q9Z0E8 (UniProt | EBI)

Last sequence update: 1999-05-01
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Organic cation/carnitine transporter 2;AltName: Full=High-affinity sodium-dependent carnitine cotransporter;AltName: Full=Solute carrier family 22 member 5;

Provider

SWISS-PROT

Sequence

Polypeptide 557 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Slc22a5	solute carrier family 22 (organic cation transporter), member 5	57	105	4	10

Sequence references in MGI

J:51313 Lu Km, et al., A missense mutation of mouse OCTN2, a sodium-dependent carnitine cotransporter, in the juvenile visceral steatosis mouse. Biochem Biophys Res Commun. 1998 Nov 27;252(3):590-4
J:51918 Nezu J, et al., Primary systemic carnitine deficiency is caused by mutations in a gene encoding sodium ion-dependent carnitine transporter. Nat Genet. 1999 Jan;21(1):91-4
J:66383 Tamai I, et al., Molecular and functional characterization of organic Cation/Carnitine transporter family in mice. J Biol Chem. 2000 Dec 22;275(51):40064-72
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:150396 Kato Y, et al., PDZK1 directly regulates the function of organic cation/carnitine transporter OCTN2. Mol Pharmacol. 2005 Mar;67(3):734-43
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:328867 Fujiya M, et al., Cytokine regulation of OCTN2 expression and activity in small and large intestine. Inflamm Bowel Dis. 2011 Apr;17(4):907-16
J:328981 Wu X, et al., Functional characteristics and tissue distribution pattern of organic cation transporter 2 (OCTN2), an organic cation/carnitine transporter. J Pharmacol Exp Ther. 1999 Sep;290(3):1482-92