Sequence Detail

ID/Version

Q9WV54 (UniProt | EBI)

Last sequence update: 1999-11-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Acid ceramidase {ECO:0000305}; Short=AC; Short=ACDase; Short=Acid CDase; EC=3.5.1.23 {ECO:0000269|PubMed:9653654};AltName: Full=Acylsphingosine deacylase;AltName: Full=N-acylethanolamine hydrolase ASAH1 {ECO:0

Provider

SWISS-PROT

Sequence

Polypeptide 394 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Asah1	N-acylsphingosine amidohydrolase 1	52	102	4	40

Sequence references in MGI

J:48336 Li CM, et al., Cloning and characterization of the full-length cDNA and genomic sequences encoding murine acid ceramidase. Genomics. 1998 Jun 1;50(2):267-74
J:74647 Li CM, et al., Insertional mutagenesis of the mouse acid ceramidase gene leads to early embryonic lethality in homozygotes and progressive lipid storage disease in heterozygotes. Genomics. 2002 Feb;79(2):218-24
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:199833 Gulbins E, et al., Acid sphingomyelinase-ceramide system mediates effects of antidepressant drugs. Nat Med. 2013 Jul;19(7):934-8
J:269643 Strelow A, et al., Overexpression of acid ceramidase protects from tumor necrosis factor-induced cell death. J Exp Med. 2000 Sep 4;192(5):601-12
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89