Sequence Detail

ID/Version

Q9WV08 Q3TZS9 (UniProt | EBI)

Last sequence update: 1999-11-01
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Apelin receptor;AltName: Full=Angiotensin receptor-like 1;AltName: Full=G-protein coupled receptor APJ;AltName: Full=MSR;

Provider

SWISS-PROT

Sequence

Polypeptide 377 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Aplnr	apelin receptor	48	106	4	21

Sequence references in MGI

J:56817 Devic E, et al., Amino acid sequence and embryonic expression of msr/apj, the mouse homolog of Xenopus X-msr and human APJ. Mech Dev. 1999 Jun;84(1-2):199-203
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:243623 Freyer L, et al., Loss of Apela Peptide in Mice Causes Low Penetrance Embryonic Lethality and Defects in Early Mesodermal Derivatives. Cell Rep. 2017 Aug 29;20(9):2116-2130
J:244834 Ho L, et al., ELABELA deficiency promotes preeclampsia and cardiovascular malformations in mice. Science. 2017 Aug 18;357(6352):707-713
J:245878 Sharma B, et al., Alternative Progenitor Cells Compensate to Rebuild the Coronary Vasculature in Elabela- and Apj-Deficient Hearts. Dev Cell. 2017 Sep 25;42(6):655-666.e3
J:261072 Sato T, et al., ELABELA-APJ axis protects from pressure overload heart failure and angiotensin II-induced cardiac damage. Cardiovasc Res. 2017 Jun 1;113(7):760-769