Sequence Detail

ID/Version

Q9WV07 B1ASX3 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Hydroperoxide isomerase ALOXE3 {ECO:0000305};AltName: Full=Epidermis-type lipoxygenase 3 {ECO:0000303|PubMed:10366447}; Short=Epidermal LOX-3; Short=e-LOX-3 {ECO:0000303|PubMed:10366447}; Short=eLOX-3;AltName: Full=Hy

Provider

SWISS-PROT

Sequence

Polypeptide 711 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Aloxe3	arachidonate lipoxygenase 3	67	100	3	11

Sequence references in MGI

J:51789 Kinzig A, et al., cDNA cloning, genomic structure, and chromosomal localization of a novel murine epidermis-type lipoxygenase. Genomics. 1999 Jun 1;58(2):158-64
J:116329 Yu Z, et al., Human and mouse eLOX3 have distinct substrate specificities: implications for their linkage with lipoxygenases in skin. Arch Biochem Biophys. 2006 Nov 15;455(2):188-96
J:162784 Hallenborg P, et al., Epidermis-type lipoxygenase 3 regulates adipocyte differentiation and peroxisome proliferator-activated receptor gamma activity. Mol Cell Biol. 2010 Aug;30(16):4077-91
J:196489 Krieg P, et al., Aloxe3 knockout mice reveal a function of epidermal lipoxygenase-3 as hepoxilin synthase and its pivotal role in barrier formation. J Invest Dermatol. 2013 Jan;133(1):172-80