Sequence Detail

ID/Version

Q9WUX5 Q3U069 Q9R2C5 (UniProt | EBI)

Last sequence update: 2007-10-02
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Inositol 1,4,5-triphosphate receptor associated 1 {ECO:0000305};AltName: Full=Inositol 1,4,5-trisphosphate receptor-associated cGMP kinase substrate;AltName: Full=JAW1-related protein MRVI1;AltName: Full=Murine retrovirus integration site 1

Provider

SWISS-PROT

Sequence

Polypeptide 899 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Irag1	inositol 1,4,5-triphosphate receptor associated 1	12	99	3	13

Sequence references in MGI

J:54295 Shaughnessy JD Jr, et al., Mrvi1, a common MRV integration site in BXH2 myeloid leukemias, encodes a protein with homology to a lymphoid-restricted membrane protein Jaw1. Oncogene. 1999 Mar 25;18(12):2069-84
J:94387 Geiselhoringer A, et al., IRAG is essential for relaxation of receptor-triggered smooth muscle contraction by cGMP kinase. EMBO J. 2004 Oct 27;23(21):4222-31
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:180467 Antl M, et al., IRAG mediates NO/cGMP-dependent inhibition of platelet aggregation and thrombus formation. Blood. 2007 Jan 15;109(2):552-9
J:292477 Peters CH, et al., Isoform-specific regulation of HCN4 channels by a family of endoplasmic reticulum proteins. Proc Natl Acad Sci U S A. 2020 Jul 28;117(30):18079-18090
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89