Sequence Detail

ID/Version

Q9WUL5 (UniProt | EBI)

Last sequence update: 1999-11-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Programmed cell death 1 ligand 2; Short=PD-1 ligand 2; Short=PD-L2; Short=PDCD1 ligand 2; Short=Programmed death ligand 2;AltName: Full=Butyrophilin B7-DC; Short=B7-DC;AltName: CD_antigen=CD273;Flags:

Provider

SWISS-PROT

Sequence

Polypeptide 247 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Pdcd1lg2	programmed cell death 1 ligand 2	22	102	3	22

Sequence references in MGI

J:67842 Latchman Y, et al., PD-L2 is a second ligand for PD-I and inhibits T cell activation. Nat Immunol. 2001 Mar;2(3):261-8
J:68616 Tseng SY, et al., B7-DC, a new dendritic cell molecule with potent costimulatory properties for T cells. J Exp Med. 2001 Apr 2;193(7):839-46
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:139033 Lazar-Molnar E, et al., Crystal structure of the complex between programmed death-1 (PD-1) and its ligand PD-L2. Proc Natl Acad Sci U S A. 2008 Jul 29;105(30):10483-8