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Sequence Detail
Q9WUI0 Q9QZ61 (UniProt | EBI) Last sequence update: 1999-11-01
Last annotation update: 2020-06-17
from provider
RecName: Full=Homeobox protein MIXL1;AltName: Full=Homeodomain protein MIX; Short=mMix;AltName: Full=MIX1 homeobox-like protein 1;AltName: Full=Mix.1 homeobox-like protein;
Polypeptide 231 aa
For this sequence
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Orthologs Phenotypic
Gene Mixl1 Mix1 homeobox-like 1 (Xenopus laevis) 34 80 4 6
Sequence references in MGI J:41442 Pearce JJ, et al., Mml, a mouse mix-like gene expressed in the primitive streak. Mech Dev. 1999 Sep;87(1-2):189-92
J:65842 Robb L, et al., Cloning, expression analysis, and chromosomal localization of murine and human homologues of a xenopus mix gene. Dev Dyn. 2000 Dec;219(4):497-504
J:77443 Hart AH, et al., Mixl1 is required for axial mesendoderm morphogenesis and patterning in the murine embryo. Development. 2002 Aug;129(15):3597-608
J:77930 Sahr K, et al., Structure, upstream promoter region, and functional domains of a mouse and human Mix paired-like homeobox gene. Gene. 2002 May 29;291(1-2):135-47
J:117059 Tam PP, et al., Sequential allocation and global pattern of movement of the definitive endoderm in the mouse embryo during gastrulation. Development. 2007 Jan;134(2):251-60
J:123041 Izzi L, et al., Foxh1 recruits Gsc to negatively regulate Mixl1 expression during early mouse development. EMBO J. 2007 Jul 11;26(13):3132-43
J:131238 Willey S, et al., Acceleration of mesoderm development and expansion of hematopoietic progenitors in differentiating ES cells by the mouse Mix-like homeodomain transcription factor. Blood. 2006 Apr 15;107(8):3122-30
J:202591 Mohn D, et al., Mouse Mix gene is activated early during differentiation of ES and F9 stem cells and induces endoderm in frog embryos. Dev Dyn. 2003 Mar;226(3):446-59

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.15
The Jackson Laboratory