Sequence Detail

ID/Version

Q9WUB6 Q8VCF8 A2ADB6 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Chloride channel protein ClC-Kb; Short=Chloride channel Kb;AltName: Full=ClC-K2 {ECO:0000303|PubMed:27335120};

Provider

SWISS-PROT

Sequence

Polypeptide 687 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Clcnkb	chloride channel, voltage-sensitive Kb	31	98	4	11

Sequence references in MGI

J:114790 Estevez R, et al., Barttin is a Cl- channel beta-subunit crucial for renal Cl- reabsorption and inner ear K+ secretion. Nature. 2001 Nov 29;414(6863):558-61
J:259639 Hennings JC, et al., The ClC-K2 Chloride Channel Is Critical for Salt Handling in the Distal Nephron. J Am Soc Nephrol. 2017 Jan;28(1):209-217
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:316474 Lin MH, et al., Impairment in renal medulla development underlies salt wasting in Clc-k2 channel deficiency. JCI Insight. 2021 Oct 22;6(20):e151039
J:349393 Pyrshev K, et al., ClC-K2 Cl(-) channel allows identification of A- and B-type of intercalated cells in split-opened collecting ducts. FASEB J. 2022 May;36(5):e22275