Sequence Detail

ID/Version

Q9WU78 O89014 Q8BSL8 Q99LR3 Q8R0H5 Q9QZN8 O88695 Q3TED2 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Programmed cell death 6-interacting protein {ECO:0000305};AltName: Full=ALG-2-interacting protein 1;AltName: Full=ALG-2-interacting protein X;AltName: Full=E2F1-inducible protein;AltName: Full=Eig2;

Provider

SWISS-PROT

Sequence

Polypeptide 869 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Pdcd6ip	programmed cell death 6 interacting protein	52	102	3	12

Sequence references in MGI

J:52190 Vito P, et al., Cloning of AIP1, a novel protein that associates with the apoptosis-linked gene ALG-2 in a Ca2+-dependent reaction. J Biol Chem. 1999 Jan 15;274(3):1533-40
J:53664 Missotten M, et al., Alix, a novel mouse protein undergoing calcium-dependent interaction with the apoptosis-linked-gene 2 (ALG-2) protein. Cell Death Differ. 1999 Feb;6(2):124-9
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:193448 Baietti MF, et al., Syndecan-syntenin-ALIX regulates the biogenesis of exosomes. Nat Cell Biol. 2012 Jul;14(7):677-85
J:237678 Romancino DP, et al., Identification and characterization of the nano-sized vesicles released by muscle cells. FEBS Lett. 2013 May 02;587(9):1379-84
J:238436 Campos Y, et al., Alix-mediated assembly of the actomyosin-tight junction polarity complex preserves epithelial polarity and epithelial barrier. Nat Commun. 2016 Jun 23;7:11876
J:245241 Murrow L, et al., ATG12-ATG3 interacts with Alix to promote basal autophagic flux and late endosome function. Nat Cell Biol. 2015 Mar;17(3):300-10
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89