Sequence Detail

ID/Version

Q9WTZ2 Q6PG67 (UniProt | EBI)

Last sequence update: 1999-11-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Membrane-bound transcription factor site-1 protease {ECO:0000305}; EC=3.4.21.112 {ECO:0000269|PubMed:9990022};AltName: Full=Endopeptidase S1P;AltName: Full=Sterol-regulated luminal protease;AltName: Full=Subtilisin/kexin isozyme 1 {E

Provider

SWISS-PROT

Sequence

Polypeptide 1052 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Mbtps1	membrane-bound transcription factor peptidase, site 1	42	102	3	41

Sequence references in MGI

J:53067 Seidah NG, et al., Mammalian subtilisin/kexin isozyme SKI-1: A widely expressed proprotein convertase with a unique cleavage specificity and cellular localization. Proc Natl Acad Sci U S A. 1999 Feb 16;96(4):1321-6
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:336735 Chen X, et al., Proteolytic processing of secretory pathway kinase Fam20C by site-1 protease promotes biomineralization. Proc Natl Acad Sci U S A. 2021 Aug 10;118(32)