Sequence Detail

ID/Version

Q9WTI7 O08571 Q5ND48 Q5ND49 Q3U231 Q3TBQ4 Q9ERB6 O08834 Q5ND46 Q9QW54 (UniProt | EBI)

Last sequence update: 2009-04-14
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Unconventional myosin-Ic;AltName: Full=Myosin I beta; Short=MMI-beta; Short=MMIb;

Provider

SWISS-PROT

Sequence

Polypeptide 1063 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Myo1c	myosin IC	93	98	4	29

Sequence references in MGI

J:4139 Sherr EH, et al., Mammalian myosin I alpha, I beta, and I gamma: new widely expressed genes of the myosin I family. J Cell Biol. 1993 Mar;120(6):1405-16
J:39118 Crozet F, et al., Cloning of the genes encoding two murine and human cochlear unconventional type I myosins. Genomics. 1997 Mar 1;40(2):332-41
J:40754 Hamilton BA, et al., The vibrator mutation causes neurodegeneration via reduced expression of PITP alpha: positional complementation cloning and extragenic suppression. Neuron. 1997 May;18(5):711-22
J:80816 Bose A, et al., Glucose transporter recycling in response to insulin is facilitated by myosin Myo1c. Nature. 2002 Dec 19;420(6917):821-4
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:99802 Etournay R, et al., PHR1, an integral membrane protein of the inner ear sensory cells, directly interacts with myosin 1c and myosin VIIa. J Cell Sci. 2005 Jul 1;118(Pt 13):2891-9
J:100987 Stauffer EA, et al., Fast adaptation in vestibular hair cells requires Myosin-1c activity. Neuron. 2005 Aug 18;47(4):541-53
J:117964 Hokanson DE, et al., Myo1c binds phosphoinositides through a putative pleckstrin homology domain. Mol Biol Cell. 2006 Nov;17(11):4856-65
J:132430 Holt JR, et al., A chemical-genetic strategy implicates myosin-1c in adaptation by hair cells. Cell. 2002 Feb 8;108(3):371-81
J:199747 Boguslavsky S, et al., Myo1c binding to submembrane actin mediates insulin-induced tethering of GLUT4 vesicles. Mol Biol Cell. 2012 Oct;23(20):4065-78
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:235308 Yu NK, et al., A transducible nuclear/nucleolar protein, mLLP, regulates neuronal morphogenesis and synaptic transmission. Sci Rep. 2016;6:22892
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89