About   Help   FAQ
Sequence Detail
Q9R229 A6H6S5 Q9Z1V8 (UniProt | EBI) Last sequence update: 2007-11-13
Last annotation update: 2018-02-28
from provider
RecName: Full=Bone morphogenetic protein 10; Short=BMP-10;Flags: Precursor;
Polypeptide 421 aa
For this sequence
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Orthologs Phenotypic
Gene Bmp10 bone morphogenetic protein 10 46 8 9 11
Sequence references in MGI J:53506 Neuhaus H, et al., Heart specific expression of mouse BMP-10 a novel member of the TGF-beta superfamily. Mech Dev. 1999 Feb;80(2):181-4
J:89404 Pashmforoush M, et al., Nkx2-5 pathways and congenital heart disease; loss of ventricular myocyte lineage specification leads to progressive cardiomyopathy and complete heart block. Cell. 2004 Apr 30;117(3):373-86
J:89476 Chen H, et al., BMP10 is essential for maintaining cardiac growth during murine cardiogenesis. Development. 2004 May;131(9):2219-31
J:116941 Chen H, et al., Overexpression of bone morphogenetic protein 10 in myocardium disrupts cardiac postnatal hypertrophic growth. J Biol Chem. 2006 Sep 15;281(37):27481-91
J:176620 Castonguay R, et al., Soluble endoglin specifically binds bone morphogenetic proteins 9 and 10 via its orphan domain, inhibits blood vessel formation, and suppresses tumor growth. J Biol Chem. 2011 Aug 26;286(34):30034-46

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
MGI 6.12
The Jackson Laboratory