Sequence Detail

ID/Version

Q9R226 O88624 (UniProt | EBI)

Last sequence update: 2000-05-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=KH domain-containing, RNA-binding, signal transduction-associated protein 3;AltName: Full=RNA-binding protein Etoile;AltName: Full=Sam68-like mammalian protein 2; Short=SLM-2;

Provider

SWISS-PROT

Sequence

Polypeptide 346 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Khdrbs3	KH domain containing, RNA binding, signal transduction associated 3	31	103	3	19

Sequence references in MGI

J:53497 Di Fruscio M, et al., Characterization of Sam68-like mammalian proteins SLM-1 and SLM-2: SLM-1 is a Src substrate during mitosis. Proc Natl Acad Sci U S A. 1999 Mar 16;96(6):2710-5
J:55377 Venables JP, et al., T-STAR/ETOILE: a novel relative of SAM68 that interacts with an RNA-binding protein implicated in spermatogenesis. Hum Mol Genet. 1999 Jun;8(6):959-69
J:95160 Haegebarth A, et al., The nuclear tyrosine kinase BRK/Sik phosphorylates and inhibits the RNA-binding activities of the Sam68-like mammalian proteins SLM-1 and SLM-2. J Biol Chem. 2004 Dec 24;279(52):54398-404
J:179373 Iijima T, et al., SAM68 Regulates Neuronal Activity-Dependent Alternative Splicing of Neurexin-1. Cell. 2011 Dec 23;147(7):1601-14
J:199861 Ehrmann I, et al., The tissue-specific RNA binding protein T-STAR controls regional splicing patterns of neurexin pre-mRNAs in the brain. PLoS Genet. 2013 Apr;9(4):e1003474
J:208331 Iijima T, et al., Neuronal cell type-specific alternative splicing is regulated by the KH domain protein SLM1. J Cell Biol. 2014 Feb 3;204(3):331-42
J:218840 Traunmuller L, et al., Alternative splicing coupled nonsense-mediated decay generates neuronal cell type-specific expression of SLM proteins. J Neurosci. 2014 Dec 10;34(50):16755-61
J:232552 Traunmuller L, et al., Control of neuronal synapse specification by a highly dedicated alternative splicing program. Science. 2016 May 20;352(6288):982-6