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Sequence Detail
ID/Version
Q9R1X5 O88284 Q5CZY2 (UniProt | EBI) Last sequence update: 2011-06-28
Last annotation update: 2024-03-27
Sequence
description
from provider
RecName: Full=ATP-binding cassette sub-family C member 5; EC=7.6.2.- {ECO:0000269|PubMed:17229149}; EC=7.6.2.2 {ECO:0000250|UniProtKB:O15440};AltName: Full=Multi-specific organic anion transporter C; Short=MOAT-C;AltName: Full=Mult
Provider SWISS-PROT
Sequence
Polypeptide 1436 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Abcc5 ATP-binding cassette, sub-family C member 5 50 99 3 55
Sequence references in MGI J:59274 Suzuki T, et al., Detailed structural analysis on both human MRP5 and mouse mrp5 transcripts. Gene. 2000 Jan 25;242(1-2):167-73
J:107028 Soontornmalai A, et al., Differential, strain-specific cellular and subcellular distribution of multidrug transporters in murine choroid plexus and blood-brain barrier. Neuroscience. 2006;138(1):159-69
J:135561 de Wolf CJ, et al., cGMP transport by vesicles from human and mouse erythrocytes. FEBS J. 2007 Jan;274(2):439-50
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:215247 Korolnek T, et al., Control of metazoan heme homeostasis by a conserved multidrug resistance protein. Cell Metab. 2014 Jun 3;19(6):1008-19
J:275364 Jansen RS, et al., ATP-binding Cassette Subfamily C Member 5 (ABCC5) Functions as an Efflux Transporter of Glutamate Conjugates and Analogs. J Biol Chem. 2015 Dec 18;290(51):30429-40
J:279737 Cyranka M, et al., Abcc5 Knockout Mice Have Lower Fat Mass and Increased Levels of Circulating GLP-1. Obesity (Silver Spring). 2019 Aug;27(8):1292-1304
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory