Sequence Detail

ID/Version

Q9R1V4 A2AUA8 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Disintegrin and metalloproteinase domain-containing protein 11; Short=ADAM 11;AltName: Full=Metalloproteinase-like, disintegrin-like, and cysteine-rich protein; Short=MDC;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 773 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Adam11	a disintegrin and metallopeptidase domain 11	22	103	3	10

Sequence references in MGI

J:56924 Sagane K, et al., Cloning and chromosomal mapping of mouse ADAM11, ADAM22 and ADAM23. Gene. 1999 Aug 5;236(1):79-86
J:80252 Rybnikova E, et al., Developmental regulation and neuronal expression of the cellular disintegrin ADAM11 gene in mouse nervous system. Neuroscience. 2002;112(4):921-34
J:107127 Takahashi E, et al., Deficits in spatial learning and motor coordination in ADAM11-deficient mice. BMC Neurosci. 2006;7:19
J:110471 Takahashi E, et al., Altered nociceptive response in ADAM11-deficient mice. Brain Res. 2006 Jun 30;1097(1):39-42
J:153391 Sagane K, et al., LGI1 and LGI4 bind to ADAM22, ADAM23 and ADAM11. Int J Biol Sci. 2008;4(6):387-96
J:226018 Kole MJ, et al., Selective Loss of Presynaptic Potassium Channel Clusters at the Cerebellar Basket Cell Terminal Pinceau in Adam11 Mutants Reveals Their Role in Ephaptic Control of Purkinje Cell Firing. J Neurosci. 2015 Aug 12;35(32):11433-44