Sequence Detail

ID/Version

Q9R1R2 Q3UMU5 (UniProt | EBI)

Last sequence update: 2000-05-01
Last annotation update: 2025-06-18

Sequence description from provider

RecName: Full=Tripartite motif-containing protein 3; EC=2.3.2.27 {ECO:0000250|UniProtKB:O75382};AltName: Full=RING finger protein 22;AltName: Full=RING finger protein HAC1;

Provider

SWISS-PROT

Sequence

Polypeptide 744 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Trim3	tripartite motif-containing 3	39	103	4	10

Sequence references in MGI

J:69273 Reymond A, et al., The tripartite motif family identifies cell compartments. EMBO J. 2001 May 1;20(9):2140-51
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:207738 Labonte D, et al., TRIM3 regulates the motility of the kinesin motor protein KIF21B. PLoS One. 2013;8(9):e75603
J:237577 Schreiber J, et al., Ubiquitin ligase TRIM3 controls hippocampal plasticity and learning by regulating synaptic gamma-actin levels. J Cell Biol. 2015 Nov 09;211(3):569-86
J:263376 Trinidad JC, et al., Comprehensive identification of phosphorylation sites in postsynaptic density preparations. Mol Cell Proteomics. 2006 May;5(5):914-22
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:296221 Li WW, et al., Ubiquitination of TLR3 by TRIM3 signals its ESCRT-mediated trafficking to the endolysosomes for innate antiviral response. Proc Natl Acad Sci U S A. 2020 Sep 22;117(38):23707-23716