Sequence Detail

ID/Version

Q9R1P4 (UniProt | EBI)

Last sequence update: 2000-05-01
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Proteasome subunit alpha type-1;AltName: Full=Macropain subunit C2;AltName: Full=Multicatalytic endopeptidase complex subunit C2;AltName: Full=Proteasome component C2;AltName: Full=Proteasome nu chain;

Provider

SWISS-PROT

Sequence

Polypeptide 263 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Psma1	proteasome subunit alpha 1	20	100	3	9

Sequence references in MGI

J:57232 Elenich LA, et al., The complete primary structure of mouse 20S proteasomes. Immunogenetics. 1999 Sep;49(10):835-42
J:60011 Hopitzan A, et al., The mouse psma1 gene coding for the alpha-type C2 proteasome subunit: structural and functional analysis, mapping, and colocalization with pde3b on mouse chromosome 7. Genomics. 2000 Jun 15;66(3):313-23
J:107084 Cui F, et al., The up-regulation of proteasome subunits and lysosomal proteases in hepatocellular carcinomas of the HBx gene knockin transgenic mice. Proteomics. 2006 Jan;6(2):498-504
J:107376 Khor B, et al., Proteasome activator PA200 is required for normal spermatogenesis. Mol Cell Biol. 2006 Apr;26(8):2999-3007
J:155590 Martinez-Solano L, et al., Proteomics of RAW 264.7 macrophages upon interaction with heat-inactivated Candida albicans cells unravel an anti-inflammatory response. Proteomics. 2009 Jun;9(11):2995-3010
J:156236 Qureshi N, et al., The proteasome as a lipopolysaccharide-binding protein in macrophages: differential effects of proteasome inhibition on lipopolysaccharide-induced signaling events. J Immunol. 2003 Aug 1;171(3):1515-25
J:181547 Huber EM, et al., Immuno- and constitutive proteasome crystal structures reveal differences in substrate and inhibitor specificity. Cell. 2012 Feb 17;148(4):727-38
J:188902 Gomes AV, et al., Mapping the murine cardiac 26S proteasome complexes. Circ Res. 2006 Aug 18;99(4):362-71
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89