Sequence Detail

ID/Version

Q9R1I1 Q9WUE5 (UniProt | EBI)

Last sequence update: 2000-05-01
Last annotation update: 2023-11-08

Sequence description from provider

RecName: Full=Carbohydrate sulfotransferase 4; EC=2.8.2.- {ECO:0000269|PubMed:10435581, ECO:0000269|PubMed:16227985};AltName: Full=Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 3; Short=GST-3;AltName: Full=High end

Provider

SWISS-PROT

Sequence

Polypeptide 388 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Chst4	carbohydrate sulfotransferase 4	16	100	2	4

Sequence references in MGI

J:57381 Hiraoka N, et al., A novel, high endothelial venule-specific sulfotransferase expresses 6-sulfo sialyl Lewis(x), an L-selectin ligand displayed by CD34. Immunity. 1999 Jul;11(1):79-89
J:58141 Bistrup A, et al., Sulfotransferases of two specificities function in the reconstitution of high endothelial cell ligands for L-selectin. J Cell Biol. 1999 May 17;145(4):899-910
J:86460 van Zante A, et al., Lymphocyte-HEV interactions in lymph nodes of a sulfotransferase-deficient mouse. J Exp Med. 2003 Nov 3;198(9):1289-300
J:86759 Hemmerich S, et al., Sulfation of L-selectin ligands by an HEV-restricted sulfotransferase regulates lymphocyte homing to lymph nodes. Immunity. 2001 Aug;15(2):237-47
J:95268 Gauguet JM, et al., Core 2 branching beta1,6-N-acetylglucosaminyltransferase and high endothelial cell N-acetylglucosamine-6-sulfotransferase exert differential control over B- and T-lymphocyte homing to peripheral lymph nodes. Blood. 2004 Dec 15;104(13):4104-12
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:112598 Kawashima H, et al., N-acetylglucosamine-6-O-sulfotransferases 1 and 2 cooperatively control lymphocyte homing through L-selectin ligand biosynthesis in high endothelial venules. Nat Immunol. 2005 Nov;6(11):1096-104
J:112599 Uchimura K, et al., A major class of L-selectin ligands is eliminated in mice deficient in two sulfotransferases expressed in high endothelial venules. Nat Immunol. 2005 Nov;6(11):1105-13
J:113195 Hiraoka N, et al., Core 2 branching beta1,6-N-acetylglucosaminyltransferase and high endothelial venule-restricted sulfotransferase collaboratively control lymphocyte homing. J Biol Chem. 2004 Jan 23;279(4):3058-67