Sequence Detail

ID/Version

Q9R0T8 Q8C2I3 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Inhibitor of nuclear factor kappa-B kinase subunit epsilon; Short=I-kappa-B kinase epsilon; Short=IKK-E; Short=IKK-epsilon; Short=IkBKE; EC=2.7.11.10 {ECO:0000269|PubMed:10421793};AltName: Full=Inducib

Provider

SWISS-PROT

Sequence

Polypeptide 717 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Ikbke	inhibitor of kappaB kinase epsilon	42	98	3	10

Sequence references in MGI

J:66314 Shimada T, et al., IKK-i, a novel lipopolysaccharide-inducible kinase that is related to IkappaB kinases. Int Immunol. 1999 Aug;11(8):1357-62
J:91363 Hemmi H, et al., The Roles of Two IkappaB Kinase-related Kinases in Lipopolysaccharide and Double Stranded RNA Signaling and Viral Infection. J Exp Med. 2004 Jun 21;199(12):1641-50
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:119791 Tenoever BR, et al., Multiple functions of the IKK-related kinase IKKepsilon in interferon-mediated antiviral immunity. Science. 2007 Mar 2;315(5816):1274-8
J:153893 Chiang SH, et al., The protein kinase IKKepsilon regulates energy balance in obese mice. Cell. 2009 Sep 4;138(5):961-75
J:178837 Perwitasari O, et al., Inhibitor of kappaB Kinase {epsilon} (IKK{epsilon}), STAT1, and IFIT2 Proteins Define Novel Innate Immune Effector Pathway against West Nile Virus Infection. J Biol Chem. 2011 Dec 30;286(52):44412-23
J:180134 Ng SL, et al., IkappaB kinase epsilon (IKK(epsilon)) regulates the balance between type I and type II interferon responses. Proc Natl Acad Sci U S A. 2011 Dec 27;108(52):21170-5