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Sequence Detail
ID/Version
Q9R0M5 Q3UWB5 Q8CEE8 Q8CAB5 Q8R1Q6 (UniProt | EBI) Last sequence update: 2000-05-01
Last annotation update: 2025-02-05
Sequence
description
from provider
RecName: Full=Thiamine pyrophosphokinase 1 {ECO:0000305|PubMed:38547260}; Short=mTPK1 {ECO:0000303|PubMed:10567383}; EC=2.7.6.- {ECO:0000250|UniProtKB:Q9H3S4};AltName: Full=Thiamin pyrophosphokinase 1 {ECO:0000303|PubMed:10567383};
Provider SWISS-PROT
Sequence
Polypeptide 243 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Tpk1 thiamine pyrophosphokinase 30 99 3 9
Sequence references in MGI J:58779 Nosaka K, et al., Molecular cloning and expression of a mouse thiamin pyrophosphokinase cDNA. J Biol Chem. 1999 Nov 26;274(48):34129-33
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:110308 Liu JY, et al., Pyrithiamine as a substrate for thiamine pyrophosphokinase. J Biol Chem. 2006 Mar 10;281(10):6601-7
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:347303 Sahu U, et al., Pyrimidines maintain mitochondrial pyruvate oxidation to support de novo lipogenesis. Science. 2024 Mar 29;383(6690):1484-1492

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory