Sequence Detail

ID/Version

Q9R0C8 A2CFD7 Q7TS85 Q8BRV2 Q8CCF5 Q9JLS6 Q8R076 (UniProt | EBI)

Last sequence update: 2004-08-16
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Guanine nucleotide exchange factor VAV3; Short=VAV-3;

Provider

SWISS-PROT

Sequence

Polypeptide 847 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Vav3	vav 3 oncogene	37	99	3	11

Sequence references in MGI

J:97055 Faccio R, et al., Vav3 regulates osteoclast function and bone mass. Nat Med. 2005 Mar;11(3):284-290
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:110334 Hunter SG, et al., Essential role of Vav family guanine nucleotide exchange factors in EphA receptor-mediated angiogenesis. Mol Cell Biol. 2006 Jul;26(13):4830-42
J:148966 Sindrilaru A, et al., Wound healing defect of Vav3-/- mice due to impaired {beta}2-integrin-dependent macrophage phagocytosis of apoptotic neutrophils. Blood. 2009 May 21;113(21):5266-76
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89