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Sequence Detail
ID/Version
Q9WUZ6 Q9R043 (UniProt | EBI) Last sequence update: 1999-11-01
Last annotation update: 2024-03-27
Sequence
description
from provider
RecName: Full=C-C motif chemokine 17;AltName: Full=ABCD-2 {ECO:0000303|PubMed:10508268};AltName: Full=CC chemokine TARC;AltName: Full=Small-inducible cytokine A17;AltName: Full=Thymus and activation-regulated chemokine {ECO:0000303|PubMed:10508243};Flags:
Provider SWISS-PROT
Sequence
Polypeptide 93 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Ccl17 C-C motif chemokine ligand 17 18 102 3 12
Sequence references in MGI J:57682 Schaniel C, et al., Three chemokines with potential functions in T lymphocyte-independent and -dependent B lymphocyte stimulation. Eur J Immunol. 1999 Sep;29(9):2934-47
J:57689 Lieberam I, et al., The murine beta-chemokine TARC is expressed by subsets of dendritic cells and attracts primed CD4+ T cells. Eur J Immunol. 1999 Sep;29(9):2684-94
J:71805 Bleul CC, et al., Chemokines define distinct microenvironments in the developing thymus. Eur J Immunol. 2000 Dec;30(12):3371-9
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:159098 Alferink J, et al., Compartmentalized production of CCL17 in vivo: strong inducibility in peripheral dendritic cells contrasts selective absence from the spleen. J Exp Med. 2003 Mar 3;197(5):585-99
J:237243 Achuthan A, et al., Granulocyte macrophage colony-stimulating factor induces CCL17 production via IRF4 to mediate inflammation. J Clin Invest. 2016 Sep 01;126(9):3453-66
J:266970 Fulle L, et al., CCL17 exerts a neuroimmune modulatory function and is expressed in hippocampal neurons. Glia. 2018 Oct;66(10):2246-2261
J:267153 Hsu AT, et al., Epigenetic and transcriptional regulation of IL4-induced CCL17 production in human monocytes and murine macrophages. J Biol Chem. 2018 Jul 20;293(29):11415-11423

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory