Sequence Detail

ID/Version

Q9R016 O09122 Q8CGT2 O09121 Q9R029 P81703 (UniProt | EBI)

Last sequence update: 2018-04-25
Last annotation update: 2024-05-29

Sequence description from provider

RecName: Full=Baculoviral IAP repeat-containing protein 1e;AltName: Full=Neuronal apoptosis inhibitory protein 5;

Provider

SWISS-PROT

Sequence

Polypeptide 1403 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Naip5	NLR family, apoptosis inhibitory protein 5	35	102	2	9

Sequence references in MGI

J:37707 Scharf JM, et al., The mouse region syntenic for human spinal muscular atrophy lies within the Lgn1 critical interval and contains multiple copies of Naip exon 5. Genomics. 1996 Dec 15;38(3):405-17
J:57778 Endrizzi M, et al., Comparative sequence analysis of the mouse and human Lgn1/SMA interval. Genomics. 1999 Sep 1;60(2):137-51
J:57831 Huang S, et al., The mouse Naip gene cluster on Chromosome 13 encodes several distinct functional transcripts. Mamm Genome. 1999 Oct;10(10):1032-5
J:129300 Wright EK, et al., Naip5 affects host susceptibility to the intracellular pathogen Legionella pneumophila. Curr Biol. 2003 Jan 8;13(1):27-36
J:176197 Kofoed EM, et al., Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity. Nature. 2011 Sep 29;477(7366):592-5
J:177040 Zhao Y, et al., The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus. Nature. 2011 Sep 29;477(7366):596-600
J:182490 Dubrez-Daloz L, et al., IAPs: more than just inhibitors of apoptosis proteins. Cell Cycle. 2008 Apr 15;7(8):1036-46
J:257333 Yang X, et al., Structural basis for specific flagellin recognition by the NLR protein NAIP5. Cell Res. 2018 Jan;28(1):35-47
J:277864 Tenthorey JL, et al., The structural basis of flagellin detection by NAIP5: A strategy to limit pathogen immune evasion. Science. 2017 Nov 17;358(6365):888-893