Sequence Detail

ID/Version

Q9QZS7 Q925S5 Q9JIX1 D2KXA7 Q9ET59 Q9ESC6 Q811S5 (UniProt | EBI)

Last sequence update: 2011-03-08
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Nephrin;AltName: Full=Renal glomerulus-specific cell adhesion receptor;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 1256 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Nphs1	nephrosis 1, nephrin	45	120	3	58

Sequence references in MGI

J:62771 Holzman LB, et al., Nephrin localizes to the slit pore of the glomerular epithelial cell. Kidney Int. 1999 Oct;56(4):1481-91
J:63538 Putaala H, et al., Primary structure of mouse and rat nephrin cDNA and structure and expression of the mouse gene. J Am Soc Nephrol. 2000 Jun;11(6):991-1001
J:66970 Putaala H, et al., The murine nephrin gene is specifically expressed in kidney, brain and pancreas: inactivation of the gene leads to massive proteinuria and neonatal death. Hum Mol Genet. 2001 Jan 1;10(1):1-8
J:73142 Schwarz K, et al., Podocin, a raft-associated component of the glomerular slit diaphragm, interacts with CD2AP and nephrin. J Clin Invest. 2001 Dec;108(11):1621-9
J:78616 Hamano Y, et al., Determinants of vascular permeability in the kidney glomerulus. J Biol Chem. 2002 Aug 23;277(34):31154-62
J:140017 Komori T, et al., Expression of kin of irregular chiasm-like 3/mKirre in proprioceptive neurons of the dorsal root ganglia and its interaction with nephrin in muscle spindles. J Comp Neurol. 2008 Nov 1;511(1):92-108
J:150083 Sohn RL, et al., A role for nephrin, a renal protein, in vertebrate skeletal muscle cell fusion. Proc Natl Acad Sci U S A. 2009 Jun 9;106(23):9274-9
J:158304 Nishida K, et al., Ptf1a directly controls expression of immunoglobulin superfamily molecules Nephrin and Neph3 in the developing central nervous system. J Biol Chem. 2010 Jan 1;285(1):373-80
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:323280 Shih NY, et al., CD2AP localizes to the slit diaphragm and binds to nephrin via a novel C-terminal domain. Am J Pathol. 2001 Dec;159(6):2303-8