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Sequence Detail
ID/Version
Q9QXY6 Q8K590 (UniProt | EBI) Last sequence update: 2008-03-18
Last annotation update: 2020-08-12
Sequence
description
from provider
RecName: Full=EH domain-containing protein 3 {ECO:0000305};
Provider SWISS-PROT
Sequence
Polypeptide 535 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Ehd3 EH-domain containing 3 49 73 8 3
Sequence references in MGI J:80735 Galperin E, et al., EHD3: a protein that resides in recycling tubular and vesicular membrane structures and interacts with EHD1. Traffic. 2002 Aug;3(8):575-89
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:101755 Braun A, et al., EHD proteins associate with syndapin I and II and such interactions play a crucial role in endosomal recycling. Mol Biol Cell. 2005 Aug;16(8):3642-58
J:171715 George M, et al., Renal thrombotic microangiopathy in mice with combined deletion of endocytic recycling regulators EHD3 and EHD4. PLoS One. 2011;6(3):e17838
J:172984 Patrakka J, et al., Expression and subcellular distribution of novel glomerulus-associated proteins dendrin, ehd3, sh2d4a, plekhh2, and 2310066E14Rik. J Am Soc Nephrol. 2007 Mar;18(3):689-97
J:175049 Gudmundsson H, et al., EH domain proteins regulate cardiac membrane protein targeting. Circ Res. 2010 Jul 9;107(1):84-95
J:231243 Curran J, et al., Eps15 Homology Domain-containing Protein 3 Regulates Cardiac T-type Ca2+ Channel Targeting and Function in the Atria. J Biol Chem. 2015 May 8;290(19):12210-21
J:231244 Lu Q, et al., Early steps in primary cilium assembly require EHD1/EHD3-dependent ciliary vesicle formation. Nat Cell Biol. 2015 Mar;17(3):228-40
J:244766 Mate SE, et al., Eps homology domain endosomal transport proteins differentially localize to the neuromuscular junction. Skelet Muscle. 2012 Sep 13;2(1):19
J:247163 Curran J, et al., EHD3-dependent endosome pathway regulates cardiac membrane excitability and physiology. Circ Res. 2014 Jun 20;115(1):68-78
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/15/2020
MGI 6.15
The Jackson Laboratory