Sequence Detail

ID/Version

Q9QXX3 Q9EQK6 (UniProt | EBI)

Last sequence update: 2000-05-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Group 10 secretory phospholipase A2; EC=3.1.1.4 {ECO:0000269|PubMed:10531313, ECO:0000269|PubMed:12359733};AltName: Full=Group X secretory phospholipase A2; Short=GX sPLA2; Short=sPLA2-X;AltName: Full=Phosphatidylchol

Provider

SWISS-PROT

Sequence

Polypeptide 151 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Pla2g10	phospholipase A2, group X	90	99	3	46

Sequence references in MGI

J:58155 Valentin E, et al., On the diversity of secreted phospholipases A(2). Cloning, tissue distribution, and functional expression of two novel mouse group II enzymes. J Biol Chem. 1999 Oct 29;274(44):31195-202
J:64346 Morioka Y, et al., Mouse group X secretory phospholipase A2 induces a potent release of arachidonic acid from spleen cells and acts as a ligand for the phospholipase A2 receptor. Arch Biochem Biophys. 2000 Sep 1;381(1):31-42
J:73331 Yokota Y, et al., Clearance of group X secretory phospholipase A(2) via mouse phospholipase A(2) receptor. FEBS Lett. 2001 Dec 7;509(2):250-4
J:74678 Koduri RS, et al., Bactericidal properties of human and murine groups I, II, V, X, and XII secreted phospholipases A(2). J Biol Chem. 2002 Feb 22;277(8):5849-57
J:80718 Singer AG, et al., Interfacial kinetic and binding properties of the complete set of human and mouse groups I, II, V, X, and XII secreted phospholipases A2. J Biol Chem. 2002 Dec 13;277(50):48535-49
J:125607 Henderson WR Jr, et al., Importance of group X-secreted phospholipase A2 in allergen-induced airway inflammation and remodeling in a mouse asthma model. J Exp Med. 2007 Apr 16;204(4):865-77
J:161461 Escoffier J, et al., Group X phospholipase A2 is released during sperm acrosome reaction and controls fertility outcome in mice. J Clin Invest. 2010 May 3;120(5):1415-28
J:170945 Yamamoto K, et al., Hair follicular expression and function of group x secreted phospholipase A2 in mouse skin. J Biol Chem. 2011 Apr 1;286(13):11616-31
J:170946 Sato H, et al., Physiological Roles of Group X-secreted Phospholipase A2 in Reproduction, Gastrointestinal Phospholipid Digestion, and Neuronal Function. J Biol Chem. 2011 Apr 1;286(13):11632-48
J:238240 Schewe M, et al., Secreted Phospholipases A2 Are Intestinal Stem Cell Niche Factors with Distinct Roles in Homeostasis, Inflammation, and Cancer. Cell Stem Cell. 2016 Jul 07;19(1):38-51
J:290200 Nolin JD, et al., Secreted PLA2 group X orchestrates innate and adaptive immune responses to inhaled allergen. JCI Insight. 2017 Nov 2;2(21)