Sequence Detail

ID/Version

Q9QXW9 (UniProt | EBI)

Last sequence update: 2000-05-01
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Large neutral amino acids transporter small subunit 2;AltName: Full=L-type amino acid transporter 2; Short=mLAT2;AltName: Full=Solute carrier family 7 member 8;

Provider

SWISS-PROT

Sequence

Polypeptide 531 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Slc7a8	solute carrier family 7 (cationic amino acid transporter, y+ system), member 8	52	117	4	11

Sequence references in MGI

J:59975 Bassi MT, et al., SLC7A8, a gene mapping within the lysinuric protein intolerance critical region, encodes a new member of the glycoprotein-associated amino acid transporter family. Genomics. 1999 Dec 1;62(2):297-303
J:176748 Braun D, et al., Aminoaciduria, but normal thyroid hormone levels and signalling, in mice lacking the amino acid and thyroid hormone transporter Slc7a8. Biochem J. 2011 Oct 15;439(2):249-55
J:256844 Espino Guarch M, et al., Mutations in L-type amino acid transporter-2 support SLC7A8 as a novel gene involved in age-related hearing loss. Elife. 2018 Jan 22;7:e31511
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:335352 Knopfel EB, et al., Dysfunctional LAT2 Amino Acid Transporter Is Associated With Cataract in Mouse and Humans. Front Physiol. 2019;10:688
J:335669 Kinne A, et al., Involvement of the L-Type Amino Acid Transporter Lat2 in the Transport of 3,3'-Diiodothyronine across the Plasma Membrane. Eur Thyroid J. 2015 Sep;4(Suppl 1):42-50