Sequence Detail

ID/Version

Q9QXN3 E9QK64 Q8CAD5 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Activating signal cointegrator 1 {ECO:0000303|PubMed:12077347}; Short=ASC-1 {ECO:0000303|PubMed:12077347};AltName: Full=Thyroid receptor-interacting protein 4 {ECO:0000305}; Short=TR-interacting protein 4 {ECO:0000305};

Provider

SWISS-PROT

Sequence

Polypeptide 581 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Trip4	thyroid hormone receptor interactor 4	69	100	3	27

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:217277 Lemaire K, et al., Ubiquitin fold modifier 1 (UFM1) and its target UFBP1 protect pancreatic beta cells from ER stress-induced apoptosis. PLoS One. 2011;6(4):e18517
J:231973 Knierim E, et al., Mutations in Subunits of the Activating Signal Cointegrator 1 Complex Are Associated with Prenatal Spinal Muscular Atrophy and Congenital Bone Fractures. Am J Hum Genet. 2016 Mar 3;98(3):473-89
J:232493 Davignon L, et al., The transcription coactivator ASC-1 is a regulator of skeletal myogenesis, and its deficiency causes a novel form of congenital muscle disease. Hum Mol Genet. 2016 Apr 15;25(8):1559-73