Sequence Detail

ID/Version

Q9QXN0 Q99L16 Q3TNX1 Q9QXM9 Q6ZPP9 (UniProt | EBI)

Last sequence update: 2007-05-01
Last annotation update: 2025-06-18

Sequence description from provider

RecName: Full=Protein Shroom3;

Provider

SWISS-PROT

Sequence

Polypeptide 1986 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Shroom3	shroom family member 3	36	114	3	170

Sequence references in MGI

J:58691 Hildebrand JD, et al., Shroom, a PDZ domain-containing actin-binding protein, is required for neural tube morphogenesis in mice. Cell. 1999 Nov 24;99(5):485-97
J:86686 Okazaki N, et al., Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. DNA Res. 2003 Aug 31;10(4):167-80
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:103784 Hildebrand JD, Shroom regulates epithelial cell shape via the apical positioning of an actomyosin network. J Cell Sci. 2005 Nov 15;118(Pt 22):5191-203
J:114885 Dietz ML, et al., Differential actin-dependent localization modulates the evolutionarily conserved activity of Shroom family proteins. J Biol Chem. 2006 Jul 21;281(29):20542-54
J:197789 Mohan S, et al., Structure of Shroom domain 2 reveals a three-segmented coiled-coil required for dimerization, Rock binding, and apical constriction. Mol Biol Cell. 2012 Jun;23(11):2131-42
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89