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Sequence Detail
Q9QXK7 Q8CIM0 (UniProt | EBI) Last sequence update: 2011-07-27
Last annotation update: 2021-09-29
from provider
RecName: Full=Cleavage and polyadenylation specificity factor subunit 3; EC=3.1.27.- {ECO:0000269|PubMed:18955505};AltName: Full=Cleavage and polyadenylation specificity factor 73 kDa subunit; Short=CPSF 73 kDa subunit; Short=mRNA
Polypeptide 684 aa
For this sequence
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Orthologs Phenotypic
Gene Cpsf3 cleavage and polyadenylation specificity factor 3 23 85 2 17
Sequence references in MGI J:106894 Collart C, et al., Smicl is a novel Smad interacting protein and cleavage and polyadenylation specificity factor associated protein. Genes Cells. 2005 Sep;10(9):897-906
J:151443 Yang XC, et al., Three proteins of the U7-specific Sm ring function as the molecular ruler to determine the site of 3'-end processing in mammalian histone pre-mRNA. Mol Cell Biol. 2009 Aug;29(15):4045-56
J:156043 Yang XC, et al., Studies of the 5' exonuclease and endonuclease activities of CPSF-73 in histone pre-mRNA processing. Mol Cell Biol. 2009 Jan;29(1):31-42
J:271494 Du P, et al., An Intermediate Pluripotent State Controlled by MicroRNAs Is Required for the Naive-to-Primed Stem Cell Transition. Cell Stem Cell. 2018 Jun 1;22(6):851-864.e5
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.17
The Jackson Laboratory