Sequence Detail

ID/Version

Q9QXD6 P97323 Q3UEH1 (UniProt | EBI)

Last sequence update: 2007-01-23
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Fructose-1,6-bisphosphatase 1; Short=FBPase 1; EC=3.1.3.11 {ECO:0000250|UniProtKB:P19112};AltName: Full=D-fructose-1,6-bisphosphate 1-phosphohydrolase 1;AltName: Full=Fructose-1,6-bisphosphatase isozyme 3; Short=FBPas

Provider

SWISS-PROT

Sequence

Polypeptide 338 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Fbp1	fructose bisphosphatase 1	85	110	4	11

Sequence references in MGI

J:39731 Cloix JF, et al., Various fructose-1,6-bisphosphatase mRNAs in mouse brain, liver, kidney and heart. Neuroreport. 1997 Feb 10;8(3):617-22
J:62327 Stein S, et al., Characterization of the mouse liver fructose-1,6-bisphosphatase gene. Gene. 2001 Feb 21;264(2):215-24
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:109520 Lamont BJ, et al., Expression of human fructose-1,6-bisphosphatase in the liver of transgenic mice results in increased glycerol gluconeogenesis. Endocrinology. 2006 Jun;147(6):2764-72
J:138232 Kebede M, et al., Fructose-1,6-bisphosphatase overexpression in pancreatic beta-cells results in reduced insulin secretion: a new mechanism for fat-induced impairment of beta-cell function. Diabetes. 2008 Jul;57(7):1887-95
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89