Sequence Detail

ID/Version

Q9QWH1 B1AS98 O88463 Q8K5D9 B1ASA4 (UniProt | EBI)

Last sequence update: 2000-05-01
Last annotation update: 2026-09-02

Sequence description from provider

RecName: Full=Polyhomeotic-like protein 2; Short=mPH2;AltName: Full=Early development regulatory protein 2;AltName: Full=p36;

Provider

SWISS-PROT

Sequence

Polypeptide 850 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Phc2	polyhomeotic 2	28	101	3	46

Sequence references in MGI

J:62648 Hemenway CS, et al., The Bmi-1 oncoprotein interacts with dinG and MPh2: the role of RING finger domains. Oncogene. 1998 May 14;16(19):2541-7
J:77078 Yamaki M, et al., The mouse Edr2 (Mph2) gene has two forms of mRNA encoding 90- and 36-kDa polypeptides. Gene. 2002 Apr 17;288(1-2):103-10
J:95365 Kim MH, et al., Mph2 expression in germinal zones of the mouse brain. Dev Dyn. 2005 Jan;232(1):209-15
J:100027 Isono K, et al., Mammalian polyhomeotic homologues phc2 and phc1 act in synergy to mediate polycomb repression of hox genes. Mol Cell Biol. 2005 Aug;25(15):6694-706
J:253631 Omori Y, et al., Samd7 is a cell type-specific PRC1 component essential for establishing retinal rod photoreceptor identity. Proc Natl Acad Sci U S A. 2017 Sep 26;114(39):E8264-E8273
J:303740 Kubo S, et al., Functional analysis of Samd11, a retinal photoreceptor PRC1 component, in establishing rod photoreceptor identity. Sci Rep. 2021 Feb 18;11(1):4180
J:383960 Fanis P, et al., Five friends of methylated chromatin target of protein-arginine-methyltransferase[prmt]-1 (chtop), a complex linking arginine methylation to desumoylation. Mol Cell Proteomics. 2012 Nov;11(11):1263-73