Sequence Detail

ID/Version

Q9QUR8 O88371 (UniProt | EBI)

Last sequence update: 2000-05-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Semaphorin-7A;AltName: Full=Semaphorin-K1; Short=Sema K1;AltName: Full=Semaphorin-L; Short=Sema L;AltName: CD_antigen=CD108;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 664 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Sema7a	sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A	51	109	3	12

Sequence references in MGI

J:49735 Lange C, et al., New eukaryotic semaphorins with close homology to semaphorins of DNA viruses. Genomics. 1998 Aug 1;51(3):340-50
J:51985 Sato Y, et al., Molecular cloning and expression of murine homologue of semaphorin K1 gene. Biochim Biophys Acta. 1998 Dec 22;1443(3):419-22
J:63557 Mine T, et al., CDw108 expression during T-cell development. Tissue Antigens. 2000 May;55(5):429-36
J:87191 Pasterkamp RJ, et al., Semaphorin 7A promotes axon outgrowth through integrins and MAPKs. Nature. 2003 Jul 24;424(6947):398-405
J:113360 Czopik AK, et al., Semaphorin 7A is a negative regulator of T cell responses. Immunity. 2006 May;24(5):591-600
J:121431 Suzuki K, et al., Semaphorin 7A initiates T-cell-mediated inflammatory responses through alpha1beta1 integrin. Nature. 2007 Apr 5;446(7136):680-4
J:306378 Guo A, et al., Immunoaffinity enrichment and mass spectrometry analysis of protein methylation. Mol Cell Proteomics. 2014 Jan;13(1):372-87
J:318656 Pan Q, et al., A homozygous R148W mutation in Semaphorin 7A causes progressive familial intrahepatic cholestasis. EMBO Mol Med. 2021 Nov 8;13(11):e14563