Sequence Detail

ID/Version

Q9QUN7 Q9DBC4 Q9QUN7 (UniProt | EBI)

Last sequence update: 2000-05-01 Last annotation update: 2013-05-01

Sequence description from provider

RecName: Full=Toll-like receptor 2;AltName: CD_antigen=CD282;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 784 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Tlr2	toll-like receptor 2	94	4	6	7

Sequence references in MGI

J:55484 Heine H, et al., Cutting edge: cells that carry A null allele for toll-like receptor 2 are capable of responding to endotoxin. J Immunol. 1999 Jun 15;162(12):6971-5
J:59320 Underhill DM, et al., The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens [see comments]. Nature. 1999 Oct 21;401(6755):811-5
J:63906 Lin Y, et al., The lipopolysaccharide-activated toll-like receptor (TLR)-4 induces synthesis of the closely related receptor TLR-2 in adipocytes. J Biol Chem. 2000 Aug 11;275(32):24255-63
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:156189 Kang JY, et al., Recognition of lipopeptide patterns by Toll-like receptor 2-Toll-like receptor 6 heterodimer. Immunity. 2009 Dec 18;31(6):873-84
J:158053 Jin MS, et al., Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide. Cell. 2007 Sep 21;130(6):1071-82