Sequence Detail

ID/Version

Q9QUG9 O09004 Q80WC0 Q8BSC8 (UniProt | EBI)

Last sequence update: 2008-01-15
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=RAS guanyl-releasing protein 2;AltName: Full=Calcium and DAG-regulated guanine nucleotide exchange factor I; Short=CalDAG-GEFI;AltName: Full=F25B3.3 kinase-like protein;

Provider

SWISS-PROT

Sequence

Polypeptide 608 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Rasgrp2	RAS, guanyl releasing protein 2	15	99	3	28

Sequence references in MGI

J:50543 Kawasaki H, et al., A Rap guanine nucleotide exchange factor enriched highly in the basal ganglia [published erratum appears in Proc Natl Acad Sci U S A 1999 Jan 5;96(1):318]. Proc Natl Acad Sci U S A. 1998 Oct 27;95(22):13278-83
J:52725 Kedra D, et al., The germinal center kinase gene and a novel CDC25-like gene are located in the vicinity of the PYGM gene on 11q13. Hum Genet. 1997 Oct;100(5-6):611-9
J:77323 Ohba Y, et al., Requirement for C3G-dependent Rap1 activation for cell adhesion and embryogenesis. EMBO J. 2001 Jul 2;20(13):3333-41
J:92864 Crittenden JR, et al., CalDAG-GEFI integrates signaling for platelet aggregation and thrombus formation. Nat Med. 2004 Sep;10(9):982-986
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:122618 Bergmeier W, et al., Mice lacking the signaling molecule CalDAG-GEFI represent a model for leukocyte adhesion deficiency type III. J Clin Invest. 2007 Jun;117(6):1699-707
J:131247 Bernardi B, et al., The small GTPase Rap1b regulates the cross talk between platelet integrin alpha2beta1 and integrin alphaIIbbeta3. Blood. 2006 Apr 1;107(7):2728-35
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89