Sequence Detail

ID/Version

Q9JMK2 Q8R389 (UniProt | EBI)

Last sequence update: 2004-05-10
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Casein kinase I isoform epsilon; Short=CKI-epsilon; Short=CKIe; EC=2.7.11.1 {ECO:0000269|PubMed:19414593};

Provider

SWISS-PROT

Sequence

Polypeptide 416 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Csnk1e	casein kinase 1, epsilon	44	102	4	68

Sequence references in MGI

J:59123 Kusuda J, et al., cDNA cloning and chromosome mapping of the mouse casein kinase I epsilon gene (Csnk1e). Cytogenet Cell Genet. 1999;87(1-2):99-101
J:73655 Lee C, et al., Posttranslational mechanisms regulate the mammalian circadian clock. Cell. 2001 Dec 28;107(7):855-67
J:87576 Lee C, et al., Direct association between mouse PERIOD and CKIepsilon is critical for a functioning circadian clock. Mol Cell Biol. 2004 Jan;24(2):584-94
J:135186 Meng QJ, et al., Setting clock speed in mammals: the CK1 epsilon tau mutation in mice accelerates circadian pacemakers by selectively destabilizing PERIOD proteins. Neuron. 2008 Apr 10;58(1):78-88
J:150148 Etchegaray JP, et al., Casein kinase 1 delta regulates the pace of the mammalian circadian clock. Mol Cell Biol. 2009 Jul;29(14):3853-66
J:177139 Lee HM, et al., The period of the circadian oscillator is primarily determined by the balance between casein kinase 1 and protein phosphatase 1. Proc Natl Acad Sci U S A. 2011 Sep 27;108(39):16451-6
J:263376 Trinidad JC, et al., Comprehensive identification of phosphorylation sites in postsynaptic density preparations. Mol Cell Proteomics. 2006 May;5(5):914-22
J:306378 Guo A, et al., Immunoaffinity enrichment and mass spectrometry analysis of protein methylation. Mol Cell Proteomics. 2014 Jan;13(1):372-87
J:320154 Lee KH, et al., Phosphorylation of human enhancer filamentation 1 (HEF1) stimulates interaction with Polo-like kinase 1 leading to HEF1 localization to focal adhesions. J Biol Chem. 2018 Jan 19;293(3):847-862
J:320290 Vielhaber E, et al., Nuclear entry of the circadian regulator mPER1 is controlled by mammalian casein kinase I epsilon. Mol Cell Biol. 2000 Jul;20(13):4888-99