Sequence Detail

ID/Version

Q9JMK0 A2A5T7 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Beta-1,4-galactosyltransferase 5 {ECO:0000305}; Short=Beta-1,4-GalTase 5; Short=Beta4Gal-T5; Short=b4Gal-T5; EC=2.4.1.-;AltName: Full=Beta-1,4-GalT II {ECO:0000250|UniProtKB:O43286};AltName: Full=Glucosylceram

Provider

SWISS-PROT

Sequence

Polypeptide 388 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	B4galt5	UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 5	19	102	3	14

Sequence references in MGI

J:67774 Nakamura N, et al., Differential gene expression of beta-1,4-galactosyltransferases I, II and V during mouse brain development. J Neurochem. 2001 Jan;76(1):29-38
J:260410 Tokuda N, et al., beta4GalT6 is involved in the synthesis of lactosylceramide with less intensity than beta4GalT5. Glycobiology. 2013 Oct;23(10):1175-83
J:266295 Yoshihara T, et al., Lactosylceramide synthases encoded by B4galt5 and 6 genes are pivotal for neuronal generation and myelin formation in mice. PLoS Genet. 2018 Aug;14(8):e1007545
J:266429 Nishie T, et al., Beta4-galactosyltransferase-5 is a lactosylceramide synthase essential for mouse extra-embryonic development. Glycobiology. 2010 Oct;20(10):1311-22
J:268018 Kumagai T, et al., Involvement of murine beta-1,4-galactosyltransferase V in lactosylceramide biosynthesis. Glycoconj J. 2010 Oct;27(7-9):685-95
J:268021 Li SF, et al., Downregulation of beta1,4-galactosyltransferase 5 improves insulin resistance by promoting adipocyte commitment and reducing inflammation. Cell Death Dis. 2018 Feb 7;9(2):196