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Sequence Detail
ID/Version
Q9JMK0 A2A5T7 (UniProt | EBI) Last sequence update: 2011-07-27
Last annotation update: 2024-01-24
Sequence
description
from provider
RecName: Full=Beta-1,4-galactosyltransferase 5 {ECO:0000305}; Short=Beta-1,4-GalTase 5; Short=Beta4Gal-T5; Short=b4Gal-T5; EC=2.4.1.-;AltName: Full=Beta-1,4-GalT II {ECO:0000250|UniProtKB:O43286};AltName: Full=Glucosylceram
Provider SWISS-PROT
Sequence
Polypeptide 388 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene B4galt5 UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 5 19 102 3 14
Sequence references in MGI J:67774 Nakamura N, et al., Differential gene expression of beta-1,4-galactosyltransferases I, II and V during mouse brain development. J Neurochem. 2001 Jan;76(1):29-38
J:260410 Tokuda N, et al., beta4GalT6 is involved in the synthesis of lactosylceramide with less intensity than beta4GalT5. Glycobiology. 2013 Oct;23(10):1175-83
J:266295 Yoshihara T, et al., Lactosylceramide synthases encoded by B4galt5 and 6 genes are pivotal for neuronal generation and myelin formation in mice. PLoS Genet. 2018 Aug;14(8):e1007545
J:266429 Nishie T, et al., Beta4-galactosyltransferase-5 is a lactosylceramide synthase essential for mouse extra-embryonic development. Glycobiology. 2010 Oct;20(10):1311-22
J:268018 Kumagai T, et al., Involvement of murine beta-1,4-galactosyltransferase V in lactosylceramide biosynthesis. Glycoconj J. 2010 Oct;27(7-9):685-95
J:268021 Li SF, et al., Downregulation of beta1,4-galactosyltransferase 5 improves insulin resistance by promoting adipocyte commitment and reducing inflammation. Cell Death Dis. 2018 Feb 7;9(2):196

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/28/2024
MGI 6.13
The Jackson Laboratory