Sequence Detail

ID/Version

Q9JM51 Q3T9C5 (UniProt | EBI)

Last sequence update: 2000-10-01
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Prostaglandin E synthase; Short=mPGES-1; EC=5.3.99.3 {ECO:0000269|PubMed:10869354, ECO:0000269|PubMed:11795891};AltName: Full=Glutathione peroxidase PTGES; EC=1.11.1.- {ECO:0000250|UniProtKB:O14684};AltName: Full=Glut

Provider

SWISS-PROT

Sequence

Polypeptide 153 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Ptges	prostaglandin E synthase	34	101	3	20

Sequence references in MGI

J:65167 Murakami M, et al., Regulation of prostaglandin E2 biosynthesis by inducible membrane-associated prostaglandin E2 synthase that acts in concert with cyclooxygenase-2. J Biol Chem. 2000 Oct 20;275(42):32783-92
J:89960 Engblom D, et al., Microsomal prostaglandin E synthase-1 is the central switch during immune-induced pyresis. Nat Neurosci. 2003 Nov;6(11):1137-8
J:90980 Trebino CE, et al., Impaired inflammatory and pain responses in mice lacking an inducible prostaglandin E synthase. Proc Natl Acad Sci U S A. 2003 Jul 22;100(15):9044-9
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:285225 Lazarus M, et al., Biochemical characterization of mouse microsomal prostaglandin E synthase-1 and its colocalization with cyclooxygenase-2 in peritoneal macrophages. Arch Biochem Biophys. 2002 Jan 15;397(2):336-41
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89