Sequence Detail

ID/Version

Q9JLQ0 E9QL86 Q8K4Z1 Q8VCI9 O88903 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=CD2-associated protein;AltName: Full=Mesenchyme-to-epithelium transition protein with SH3 domains 1; Short=METS-1;

Provider

SWISS-PROT

Sequence

Polypeptide 637 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Cd2ap	CD2-associated protein	142	116	3	28

Sequence references in MGI

J:49585 Dustin ML, et al., A novel adaptor protein orchestrates receptor patterning and cytoskeletal polarity in T-cell contacts. Cell. 1998 Sep 4;94(5):667-77
J:57971 Shih NY, et al., Congenital nephrotic syndrome in mice lacking CD2-associated protein [see comments]. Science. 1999 Oct 8;286(5438):312-5
J:65183 Lehtonen S, et al., In vivo interaction of the adapter protein CD2-associated protein with the type 2 polycystic kidney disease protein, polycystin-2. J Biol Chem. 2000 Oct 20;275(42):32888-93
J:73142 Schwarz K, et al., Podocin, a raft-associated component of the glomerular slit diaphragm, interacts with CD2AP and nephrin. J Clin Invest. 2001 Dec;108(11):1621-9
J:90773 Srichai MB, et al., A WT1 co-regulator controls podocyte phenotype by shuttling between adhesion structures and nucleus. J Biol Chem. 2004 Apr 2;279(14):14398-408
J:138788 Tsui CC, et al., CD2AP and Cbl-3/Cbl-c constitute a critical checkpoint in the regulation of ret signal transduction. J Neurosci. 2008 Aug 27;28(35):8789-800
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:323280 Shih NY, et al., CD2AP localizes to the slit diaphragm and binds to nephrin via a novel C-terminal domain. Am J Pathol. 2001 Dec;159(6):2303-8