Sequence Detail

ID/Version

Q9JKF4 Q9JKF2 Q9JKF3 (UniProt | EBI)

Last sequence update: 2000-10-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=C-type lectin domain family 6 member A;AltName: Full=C-type lectin superfamily member 10;AltName: Full=Dendritic cell-associated C-type lectin 2 {ECO:0000303|PubMed:17050534}; Short=DC-associated C-type lectin 2 {ECO:0000303|PubMed:1

Provider

SWISS-PROT

Sequence

Polypeptide 209 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Clec4n	C-type lectin domain family 4, member n	9	100	5	11

Sequence references in MGI

J:143482 Barrett NA, et al., Dectin-2 recognition of house dust mite triggers cysteinyl leukotriene generation by dendritic cells. J Immunol. 2009 Jan 15;182(2):1119-28
J:152148 Robinson MJ, et al., Dectin-2 is a Syk-coupled pattern recognition receptor crucial for Th17 responses to fungal infection. J Exp Med. 2009 Aug 31;206(9):2037-51
J:160680 Saijo S, et al., Dectin-2 recognition of alpha-mannans and induction of Th17 cell differentiation is essential for host defense against Candida albicans. Immunity. 2010 May 28;32(5):681-91
J:166590 Ritter M, et al., Schistosoma mansoni triggers Dectin-2, which activates the Nlrp3 inflammasome and alters adaptive immune responses. Proc Natl Acad Sci U S A. 2010 Nov 23;107(47):20459-64
J:168200 Sato K, et al., Dectin-2 is a pattern recognition receptor for fungi that couples with the Fc receptor gamma chain to induce innate immune responses. J Biol Chem. 2006 Dec 15;281(50):38854-66
J:291457 Campuzano A, et al., CARD9-Associated Dectin-1 and Dectin-2 Are Required for Protective Immunity of a Multivalent Vaccine against Coccidioides posadasii Infection. J Immunol. 2020 Jun 15;204(12):3296-3306
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89