Sequence Detail

ID/Version

Q9JJX6 Q9JJX4 Q9JJX3 Q9JJX5 (UniProt | EBI)

Last sequence update: 2000-10-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=P2X purinoceptor 4; Short=P2X4;AltName: Full=ATP receptor;AltName: Full=Purinergic receptor;

Provider

SWISS-PROT

Sequence

Polypeptide 388 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	P2rx4	purinergic receptor P2X, ligand-gated ion channel 4	105	102	4	16

Sequence references in MGI

J:233215 Perez-Flores G, et al., The P2X7/P2X4 interaction shapes the purinergic response in murine macrophages. Biochem Biophys Res Commun. 2015 Nov 20;467(3):484-90
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:325893 Brock VJ, et al., P2X4 and P2X7 are essential players in basal T cell activity and Ca(2+) signaling milliseconds after T cell activation. Sci Adv. 2022 Feb 4;8(5):eabl9770
J:335509 Zhong XZ, et al., Activation of lysosomal P2X4 by ATP transported into lysosomes via VNUT/SLC17A9 using V-ATPase generated voltage gradient as the driving force. J Physiol. 2016 Aug 1;594(15):4253-66